Figure 1. solTNFR2 levels are increased after LAIV challenge in humans.
Nasal-swab specimens were recovered from children before immunization or days 2, 4, and 7 after challenge with LAIV and assessed for solTNFR2 by ELISA. (A) Representative kinetics of solTNFR2 levels after LAIV challenge in 3 different patients. Dashed line represents the limit of detection for the ELISA (7.8 pg/ml). (B) Change in solTNFR2 levels from preimmune levels to the peak levels observed after LAIV challenge in 8 separate patients. *P < 0.05.