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. Author manuscript; available in PMC: 2016 Feb 23.
Published in final edited form as: Life Sci. 2015 Jan 14;123:61–71. doi: 10.1016/j.lfs.2014.12.024

Figure 2. Progressive action potential prolongation and cellular arrhythmias during heart failure.

Figure 2

A. Representative action potentials at 1 Hz. B. APD50 is prolonged at 1 and 4 months of HF (p<0.05). C. APD90 is significantly prolonged in 4 M HF compared to 1 M HF and control (p<0.05). D. Beat-to-beat variability (representative, top) was significantly increased in 4 M HF (*p<0.05 vs. control, #p<0.05 vs. 1M HF). E. Early afterdepolarizations (representative, top) were more frequent in 4 M HF (*p<0.05 vs control).