Table 5.
Unadjusted (UOR) and Adjusted (AOR) Odds Ratios for Univariable and Multivariable Logistic Regression Models to Determine Measures of Association Between REALISM Criteria and Surgical Mortality Among Patients Undergoing Mitral Valve Operations
| High-Risk Criteria | Univariable Model | Multivariable Modela | |||
|---|---|---|---|---|---|
| UOR [95% CI] | p Value | Likelihood Ratio | AOR [95% CI] | p Value | |
| STS PROM > 12% | 10.14 [6.10–16.86] | <0.001 | 42.3 | 5.8 [4.05–8.5] | 0.001 |
| Three or more STS high-risk factors | 2.69 [2.60–3.52] | <0.001 | 4.91 | 1.54 [1.29–4.33] | 0.01 |
| Functional MR with EF < 0.40 | 0.66 [0.33–1.34] | 0.25 | 0.07 | 2.52 [0.30–2.76] | 0.07 |
| Age > 75 years with EF < 0.40 | 0.98 [0.13–7.24] | 0.98 | 1.61 | 0.3 [0.01–2.53] | 0.27 |
| Reoperation with patent grafts | 3.86 [2.20–6.68] | <0.001 | 0.28 | 1.32 [0.57–2.60] | 0.44 |
| Two or more prior chest surgeries | 0.64 [0.09–4.70] | 0.66 | 2.53 | 0.17 [0.02–1.48] | 0.09 |
Mixed effects multivariable logistic regression model for the outcome of mortality after mitral valve operations: modeled covariates include all high-risk criteria; model performance characteristics (C statistic = 0.78, PseudoR2 = 0.18).
CI = confidence interval; EF = ejection fraction; MR = mitral regurgitation; PROM = Predicted Risk of Mortality; STS = The Society of Thoracic Surgeons.