Figure 8. Antagomir inhibition of miR-181a dampens EAE induction.
Wild-type mice were immunized with 100 μg MOG in CFA to induce EAE and treated on days 1 and 3 post-immunization with either 80 mg/kg miR-181a antagomir or saline control. Mice were scored daily for clinical signs of EAE (n=10 for each group). A representative plot from three independent experiments is shown.