Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ability of 50 or 100 µM ciprofloxacin (Cipro) or 50 or 100 µM 8-H-moxi to compete out DNA cleavage induced by 50 µM 8-methoxy-cipro with mutant GyrAD94G Mycobacterium tuberculosis gyrase. Cipro or 8-H-moxi and 8-methoxy-cipro were added to reaction mixtures simultaneously. The low level of cleavage seen in the presence of ciprofloxacin or 8-H-moxi alone is shown at right. Ethidium bromide-stained agarose gels are shown and are representative of three independent experiments.
