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. 2016 Feb 1;113(7):1943–1948. doi: 10.1073/pnas.1519643113

Fig. 2.

Fig. 2.

Seven days of CS-US training while sodium-replete does not condition responses to a sodium CS. (A) Average dopamine concentration (±SEM) during extinction for Replete (n = 5, black) and Deplete (n = 5, red) rats. (B) Neither the CS nor the solenoid click evoked dopamine during extinction compared with baseline. (C) Approach behavior during extinction. (D) Average traces of dopamine concentration (±SEM) during reinstatement. (E) Intraoral NaCl significantly increased dopamine concentration in Deplete rats. Deplete, infusion vs. baseline or CS (**P < 0.01); Replete, no significant differences (all comparisons, P > 0.05). (F) Approach behavior during reinstatement. (G) Postrecording session sodium intake was elevated in deplete rats (*P < 0.05). Opaque bars represent the mean.