. Author manuscript; available in PMC: 2016 Feb 23.

Published in final edited form as: Biol Trace Elem Res. 2015 Jul 9;169(2):164–173. doi: 10.1007/s12011-015-0431-3

Table 4.

Analytical figures of merit

Analyte	LLOQ^a (μg/g)	ULOQ^b (μg/g)	LOD^c (μg/g)
As	0.00855	0.427	0.001
Cd	0.00214	0.427	0.001
Co	0.00427	0.427	0.0007
Cr	0.00855	0.427	0.005
Cu	0.427	8.55	0.04
Fe	21.4	214	8
Ni	0.0855	8.55	0.04
Pb	0.00427	0.427	0.0009
Zn	4.27	42.7	1

Lower limit of quantitation (LLOQ) defined as lowest matrix QC level with %RE within ±15% and %RSD ≤20% on all three validation days.

Upper limit of quantitation (ULOQ) defined as highest matrix standard included in regression.

Limit of detection (LOD) calculated as three times the standard deviation of determined concentrations for matrix QC replicates (n = 3 or 6) on the first validation day.