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. 2016 Feb 22;11(2):e0149544. doi: 10.1371/journal.pone.0149544

Table 3. Multivariate Cox regression analyses of risk factors for postoperative stage 3B CKD (eGFR < 45 mL/min/1.73 m2).

Incontinent urinary diversion was divided into 2 groups, and compared with orthotopic ileal neobladder in the model 2. Comorbidities included past history of CVD, HTN, or DM.

Variables (Model 1) Fisk factors P value HR 95%CI
Age Older than 67 years 0.043 2.90 1.03–8.13
Comorbidities Pre-existing 0.110 2.40 0.82–7.02
eGFR before surgery < 60 ml/min/1.73m2 0.020 3.25 1.20–8.80
Stent indwelling Positive 0.163 0.40 0.11–1.45
Postoperative hydronephrosis Greater than grade 1 0.002 5.15 1.81–14.6
Tumor recurrence Positive 0.900 0.91 0.22–3.71
Chemotherapy for recurrent disease Positive 0.290 0.43 0.09–2.04
Urinary diversion Incontinent diversion 0.016 4.41 1.33–14.7
Variables (Model 2)
Age Older than 67 years 0.025 3.47 1.17–10.4
Comorbidities Pre-existing 0.129 2.32 0.78–6.87
eGFR before surgery < 60 ml/min/1.73m2 0.016 3.32 1.25–8.82
Stent indwelling Positive 0.065 0.22 0.04–1.10
Postoperative hydronephrosis Greater than grade 1 0.003 4.81 1.70–13.7
Tumor recurrence Positive 0.969 0.97 0.23–4.11
Chemotherapy for recurrent disease Positive 0.196 0.33 0.06–1.77
Urinary diversion (ref. neobladder) Cutaneous ureterostomy 0.012 8.92 1.63–48.7
Ileal conduit 0.069 3.44 0.91–13.1