Figure 7.

Ischemic stroke-induced lesion is attenuated in C57BL/6J mice maintained on αTOC-deficient diet. A) Brain αTOC levels of C57BL/6J mice after 10 wk of unrestricted access to standard chow (Teklad diet #7912) or vitamin E–deficient chow (Teklad diet #88163). B) Representative T2-weighted MRI slice of C57BL/6J mouse maintained on Teklad diet #7912 or vitamin E–deficient diet #88163 at 48 h after MCAO; bar = 5 mm. C) C57BL/6J mice maintained on vitamin E–deficient diet #88163 had significantly smaller stroke-induced lesion volume compared with mice maintained on Teklad diet #7912. Data are mean ± sd, n = 11; *P < 0.05.