Table 2.

Monohexosylceramides major species in healthy corneas and diabetics (n>=3 per group).

Major MHC species were identified and quantified in human cadaver corneas from Healthy, T1DM, and T2DM donors. In healthy donors, C24:1 species were the highest followed by C24:0, C22:0, and C16:0. In T1DM, C24:1 species were also the highest followed by C16:0, C24:0, and C22:0. In T2DM, C24:1 was highest, C16:0 was second highest, followed by C24:0, and C22:0. At least three different samples from three different donors were used (n>=3).

Monohexosylceramides Species	Healthy (pmol/mg tissue)	T1DM (pmol/mg tissue)	T2DM (pmol/mg tissue)
C14:0	0.10±0.02	0.10±0.01	0.09±0.01
C16:0	0.65±0.19	0.92±0.11	0.81±0.10
C18:1	0.03±0.01	0.12±0.02	0.11±0.01
C18:0	0.43±0.09	0.43±0.06	0.40±0.05
C20:0	0.30±0.11	0.36±0.04	0.31±0.04
C22:0	0.78±0.14	0.60±0.07	0.51±0.06
C24:1	0.88±0.15	1.07±0.13	0.92±0.11
C24:0	0.80±0.12	0.87±0.10	0.75±0.09
C26:1	0.04±0.01	0.00±0.00	0.00±0.00
C26:0	0.03±0.01	0.01±0.00	0.01±0.00