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. Author manuscript; available in PMC: 2016 Feb 23.
Published in final edited form as: Vaccine. 2015 Sep 15;33(42):5553–5563. doi: 10.1016/j.vaccine.2015.09.005

Fig. 1. HPV16 L2-specific serum antibody responses in AAVLP (HPV16/31L2)-immunized mice.

Fig. 1

Groups of mice were immunized with a variety of different antigen and formulated antigen preparations as described in the methods section. Sera from mice 2 weeks post vaccination were tested for reactivity to HPV16 L2 peptides by ELISA (A) and for neutralization of HPV16 PsV (B). ELISA and neutralization activities were calculated from titration curves representing 2-fold serial dilutions of sera tested in duplicate assay wells. From these curves, the half-maximal ELISA and neutralization values for each mouse (●) were plotted for each vaccine group. Each group contained 10 mice per antigen preparation. Median and interquartile range values for each group are represented as horizontal bars.