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. 2016 Jan 15;18(3):480–483. doi: 10.1021/acs.orglett.5b03530

Table 1. Selected Data from Optimization Studya.

graphic file with name ol-2015-03530p_0006.jpg

entry catalyst temp (°C) cat. loading (% mol) yieldb
1 AuCl 50 2.5 0
2 AuCl3 50 2.5 0
3 IPrAuOAc 50 2.5 0
4 IPrAuOTs 50 2.5 34
5 IPrAuTFA 50 2.5 90
6 NaTFA 50 2.5 0
7 None 50 0 0
8 IPrAuCl 50 2.5 0
9 AgTFA 50 2.5 48
10 IPrAuTFA 50 1.0 85c
11 IPrAuTFA 50 5.0 90
12 IPrAuTFA 50 10 92
13 IPrAuTFA 25 10 89d
a

Reactions were carried out on a 0.10 mmol scale.

b

Yields were determined by the ERECTIC method using mesitylene as 1H NMR external standard.

c

23 h.

d

22 h.