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. 2016 Feb 19;11(Spec Iss):21–30. doi: 10.2147/COPD.S85978

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© 2016 Pavord et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Annual rate of exacerbations, systemic corticosteroid prescriptions, and hospitalizations in a randomized, placebo-controlled trial of combination therapy with a long-acting β-agonist and inhaled corticosteroid in patients with COPD.

Notes: *Significant difference vs placebo at the 0.05 significance level. From The New England Journal of Medicine, Calverley PM, Anderson JA, Celli B, et al, Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease, Volume 356(8), Pages 775–789. Copyright © 2007 Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.⁴⁸