Figure 2.

Effects of resveratrol supplementation on (A) atherosclerotic lesion area and (B) aortic intima/media area ratio in high cholesterol diet-fed apo E^-/- mice. Results are expressed as mean±SEM of 6 animals in each group. *, P<0.05, determined using the Mann-Whitney nonparametric test, high-dose RES-treated animals vs. control groups. Control: high cholesterol diet (#58R5) without resveratrol (RES) treatment; Low-dose RES: high cholesterol diet (#58R5)+low-dose RES supplementation; High-dose RES: high cholesterol diet (#58R5) + high-dose RES supplementation