Table 1.
Effects of resveratrol (RES) supplementation on body weight and organ weight in apo E-/- mice fed a high cholesterol diet
| Control | Low-dose RES | High-dose RES | |
|---|---|---|---|
| Initial body weight (g) | 23.99 ± 1.04 | 23.98 ± 1.04 | 24.01 ± 1.04 |
| Final body weight (g) | 26.96 ± 1.59 | 26.83 ± 1.80 | 26.15 ± 1.07 |
| Heart (g) | 0.25 ± 0.01a | 0.21 ± 0.01b | 0.20 ± 0.01b |
| Liver (g) | 1.59 ± 0.06 | 1.51 ± 0.10 | 1.50 ± 0.07 |
| Spleen (g) | 0.15 ± 0.02 | 0.12 ± 0.01 | 0.13 ± 0.01 |
| Kidney (g) | 0.37 ± 0.02 | 0.35 ± 0.04 | 0.33 ± 0.02 |
| EWAT (g) | 0.48 ± 0.10a | 0.50 ± 0.08a | 0.37 ± 0.08b |
| IL-6 (pg/ml) | 208.93 ± 26.69a | 104.63 ± 18.28b | 79.25 ± 13.42c |
1 Data are presented as means ± SEM of 6 animals in each group. Means in the same row that do not share a common superscript differ significantly (P<0.05), as determined using a one-way ANOVA test
2 Control: high cholesterol diet (#58R5) without RES treatment; Low-dose RES: high cholesterol diet (#58R5) + low-dose RES supplementation; High-dose RES: high cholesterol diet (#58R5) + high-dose RES supplementation; EWAT, epididymal white adipose tissue