Table 2.
Effect of oral resveratrol (RES) supplementation on triglycerides, total cholesterol, LDL-C, HDL-C levels, LDL/HDL-C ratio, and TC/HDL-C ratio in high cholesterol diet-fed apo E-/- mice
| Control | Low-dose RES | High-dose RES | |
|---|---|---|---|
| TG (mg/dl) | 70.67 ± 3.29 | 78.50 ± 8.91 | 76.50 ± 6.29 |
| TC (mg/dl) | 1252.67 ± 59.93 | 1326.40 ± 59.92 | 1320.51 ± 62.37 |
| LDL-C (mg/dl) | 615.43 ± 10.28a | 608.81 ± 35.86a | 565.27 ± 16.99b |
| HDL-C (mg/dl) | 47.52 ± 7.84 | 56.61 ± 12.69 | 54.85 ± 9.34 |
| LDL/HDL-C ratio | 14.08 ± 2.06a | 12.91 ± 2.34a | 11.52 ± 1.49b |
| TC/HDL-C ratio | 28.78 ± 4.62 | 27.42 ± 4.38 | 26.66 ± 4.87 |
1 Data are presented as means±SEM of 6 animals in each group. Means in the same row that do not share a common superscript differ significantly (P<0.05), as determined using a one-way ANOVA test
2 Control: high cholesterol diet (#58R5) without RES treatment; Low-dose RES: high cholesterol diet (#58R5) + low-dose RES supplementation; High-dose RES: high cholesterol diet (#58R5) + high-dose RES supplementation; Triglyceride, TG; total cholesterol, TC; low-density lipoprotein cholesterol, LDL-C; high-density lipoprotein cholesterol, HDL-C; low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio, LDL/HDL-C ratio and total cholesterol/high-density lipoprotein cholesterol, TC/HDL-C ratio