Table 2.
Histopathological examination of lung tissue
| Control | I-R | I-R+Ada | |
|---|---|---|---|
| Inflammation | 0,00±0,35 | 3,00±0,71*# | 2,00±0,46* |
| Congestion | 0,00±0,46 | 2,00±0,52*χ | 1,50±0,53* |
| Edema | 0,00±0,35 | 3,00±0,46*# | 2,00±0,52* |
| Vacuolization | 0,00±0,35 | 3,00±0,35*π | 2,00±0,52* |
| Epithelial degeneration | 0,00±0,46 | 3,00±0,52*π | 1,50±0,53* |
| Alveolar macrophages density | 0,00±0,46 | 3,50±0,74*¥ | 3,00±0,46* |
| Caspase-3 | 1,00±0,52 | 3,00±0,52*# | 2,00±0,52¶ |
I-R, Ischemia reperfusion; I-R+Ada, Ischemia reperfusion+Adalimumab
*
P<0.001,
¶
P =0.006 vs. control group
π
P<0.001,
#
P=0.001,
χ
P=0.022,
¥
P=0.038 vs. I-R+Ada group