Table 5. Diagnostic accuracy of the RT-LAMP test for EBOV compared with the reference rRT-PCR test.
RT-LAMPa | ||||
---|---|---|---|---|
trailer | NP | |||
positive | negative | positive | negative | |
rRT-PCR test (n = 100) | ||||
positive | 47 | 0 | 46 | 1 |
negative | 0 | 53 | 0 | 53 |
Diagnostic accuracy (95%CI) | ||||
Sensitivity | 100% (92.5–100) | 97.9% (88.7–100) | ||
Specificity | 100% (93.3–100) | 100%(93.3–100) | ||
Positive predictive value | 100% (92.5–100) | 100%(92.3–100) | ||
Negative predictive value | 100% (93.3–100) | 98.1%(90.1–100) |
aThe RT-LAMP test was performed in Genie III for a total of 100 RNA extracts from 44 sera and 56 swab suspensions.