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. 1977 Apr;30(4):367–371. doi: 10.1136/jcp.30.4.367

Platelet dynamics in chronic liver disease with special reference to the role of the spleen.

P J Toghill, S Green, F Ferguson
PMCID: PMC476413  PMID: 853132

Abstract

In all of 12 patients with chronic liver disease, whose platelet dynamics were investigated by the 51Cr-labelling technique in association with surface counting, platelet survival was reduced and in 11 the splenic platelet pool was increased. Surface counting showed high initial spleen liver ratios in eight patients, and in four there was evidence of progressive destruction of platelets in the spleen. In one patient, subsequently shown to have a hepatoma, progressive accumulation of platelets was noted at the tumour site.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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