Detection of the anthocyanins cyanidin-3-sambubioside and cyanidin-3-glucoside (peaks 1,2), cyanidin-3-xylosylrutinoside (peak 3), and cyanidin-3-rutinoside (peak 4) by LC MS/MS in representative OSCC biopsy tissues following short-term BRB troche administration. A, Patient PT035, 45y, stage 4 lateral tongue OSCC, never-smoker, 8-day BRB troche exposure. B, Patient PT036, 75y, stage 2 retromolar mucosa OSCC, current smoker, 7-day BRB exposure.