Table 4 . The relationship mean of the four markers with the patients' age in the case and control groups .
| Criteria | MOM | p |
| MSAFP | 1.2±0.91 | 0.437 |
| uE3 | 1±0.55 | 0.007 |
| hCG | 1.2±0.82 | 0.058 |
| Inhibin-A | 1.3±0.790 | 0.172 |
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