Table 2. Baseline functional parameters for Control Wistar and spontaneously hypertensive rats in the absence and presence of 8SPT (10-5M).
| Wistar | Wistar | SHR | SHR | |
|---|---|---|---|---|
| + 8SPT | + 8SPT | |||
| LVDP (mmHg) | 88 ± 4 | 102 ± 6 | 148 ± 14* | 138 ± 12 |
| dP/dt Max (mmHg sec-1) | 1.70 ± 0.08 | 1.92 ± 0.10 | 2.54 ± 0.23* | 2.45 ± 0.22 |
| dP/dt Min (mmHg sec-1) | 1.52 ± 0.08 | 1.80 ± 0.10 | 2.32 ± 0.17* | 2.31 ± 0.18 |
| Heart Rate (bpm) | 243 ± 11.27 | 263.4 ± 9.13 | 214 ± 18.29 | 236.4 ± 16.37 |
Abbreviations: LVDP, Left Ventricular Developed Pressure; dP/dt max/min, Ventricle max/min slope
Data represented as mean± S.E.M.
* denotes significant difference to control group (p<0.05)