Table 3. pEC₅₀ values for APNEA and CL-IB-MECA concentration response curves in the absence and presence of 8SPT (10^-5M) for control (normotensive Wistar rats) and spontaneously hypertensive rats (SHRs).

Group	Control Wistar	SHRs
APNEA	6.60 (6.13–7.07)	5.95 (5.31–6.58)*
APNEA + 8SPT	5.36 (4.85–5.88)#	4.17 (3.86–4.49)*#
CL-IB-MECA	5.369 (4.70–6.04)	5.976 (5.04–6.91)
CL-IB-MECA + 8SPT	4.73 (4.54–4.92)#	5.10 (4.65–5.54)*#

Data represented as mean (lower confidence interval-upper confidence interval).

*denotes significant difference to control group (p<0.05)

# denotes significant difference to absence of antagonist group(p<0.05)