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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Br J Haematol. 2015 Dec 18;172(5):794–806. doi: 10.1111/bjh.13862

Figure 3. Resveratrol preserves the ability of platelets to activate post-storage.

Figure 3

Human platelets were collected from healthy human donors and platelet concentrates (PC) were prepared according to standard blood banking procedures. PC were treated with vehicle (Veh), 10 μM resveratrol (Resv.), or 5 μM aspirin (ASA) prior to storage and stored for up to 5 days at room temperature with agitation. Platelets (1 × 108 platelets/ml) were washed and either left unactivated or activated with 0.2 u/ml thrombin for 15 min. Supernatants were collected and thromboxane B2 (TXB2) and prostaglandin E2 (PGE2) were assayed by enzyme immunoassy. Mean +/− SEM. n = 4 Statistical significance was determined by Two-Way RM ANOVA with Bonferroni post-test. *p<0.05, *p<0.01, ***p<0.001