Table 1.
Subject Characteristics
| Characteristic | ARDS1 (n= 86) |
ARDS2 (n=140) |
|---|---|---|
| Patient Age, mean ± SD | 50 ± 17 | 54 ± 16 |
| Male patients, no. (%) | 54 (63) | 104 (74) |
| Caucasian, no. (%) | 76 (88) | 140 (100) |
| ARDS risk factor, no. (%)a | ||
| Sepsis | 56 (65) | 113 (81) |
| Pneumonia | 36 (42) | 63 (45) |
| Trauma | 34 (39) | 0 (0) |
| Aspiration | 17 (20) | 33 (23) |
| Inhalation | 1 (1) | 0 (0) |
| Drowning | 1 (1) | 0 (0) |
| Other | 10 (12) | 46 (33) |
| APACHE score, mean ± SD | 22 ± 6 | 26±9 |
| Comorbidities, no. (%) | ||
| Diabetes | 18 (21) | 34 (24) |
| Cirrhosis | 6 (7) | 16 (11) |
| Chronic Renal Insufficiency | 2 (2) | 9 (6) |
| Circulating IL-17A pg/mL, Median (IQR) | 3.5 (1.6-9.6) | 3.7 (1.4-11.5) |
| 28-day Mortality, no. (%) | 13 (15) | 26 (18) |
| SOFA score, mean ± SDb | 9 ± 4 | 7 ± 3 |
ARDS = Acute Respiratory Distress Syndrome; APACHE = Acute Physiology and Chronic Health Evaluation; SD = standard deviation; IQR = interquartile range; IL-17A = interleukin-17A.
a
Risk factors for ARDS are not mutually exclusive
b
Highest SOFA score in first 7 days