Table 2. Multivariable Analyses.
| Outcome | Number | Hazard Ratio (95% CI) | p-value | |
|---|---|---|---|---|
|
| ||||
| TRM | ||||
|
| ||||
| Main: Chemo | 107 | 1.00 | ||
| HCT | 422 | 6.88 (3.02 – 15.70) | <0.01 | |
|
| ||||
| Age: 19 - 29 | 214 | 1.00 | ||
| 30 - 50 | 315 | 1.69 (1.16 – 2.44) | <0.01 | |
|
| ||||
| FAB: T-cell/Unspecified | 102 | 1.00 | ||
| B-cell | 427 | 2.26 (1.30 – 3.93) | <0.01 | |
|
| ||||
| Relapse | ||||
|
| ||||
| Main: Chemo | 107 | 1.00 | ||
| HCT | 422 | 1.77 (1.07 – 2.94) | 0.03 | |
|
| ||||
| CNS Involvement: No | 481 | 1.00 | ||
| Yes | 39 | 1.90 (1.07 – 3.40) | 0.03 | |
| Missing | 9 | 3.51 (1.35 – 9.16) | 0.01 | |
|
| ||||
| Treatment Failure (inverse of DFS) | ||||
|
| ||||
| Main: Chemo | 107 | 1.00 | ||
| HCT | 422 | 3.10 (2.04 – 4.70) | <0.01 | |
|
| ||||
| CNS Involvement: No | 481 | 1.00 | ||
| Yes | 39 | 1.53 (0.99 – 2.35) | 0.05 | |
| Missing | 9 | 2.21 (0.88 – 5.57) | 0.09 | |
|
| ||||
| Overall Mortality | ||||
|
| ||||
| Main: Chemo | 107 | 1.00 | ||
| HCT | 422 | 3.12 (1.99 – 4.90) | <0.01 | |
TRM: treatment related mortality; N: Number; Chemo; Chemotherapy cohort; HCT: Hematopoietic Cell Transplant; DFS: disease-free survival; OS: overall survival; CI: Confidence Interval; CNS: Central Nervous System.