Table 5.
Matrix metalloproteinase (MMP) inhibitors- note that very few are selective for specific MMPs.[88-91]
Inhibitor | MMPs inhibited |
---|---|
CGS27023A | MMP-2, MMP-3, MMP-9, MMP-12 |
matlystatin A | MMP-2, MMP-9 |
matlystatin B | MMP-2, MMP-9 |
ONO-4817 | MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12 |
Ro 28-2653 | MMP-2, MMP-9, MMP-14 |
SB-3CT | MMP-2, MMP-9 |
Doxycycline | MMP-2, MMP-9 |
Galardin | MMP-3, MMP-14 |
α1(I-III)Glyφ{PO2H-CH2}Leu THPI | MMP-9 |
RXP470.1 | MMP-12 |
Imidapril | MMP-9 |
Captopril and Ramiprilate | MMP-2 and MMP-9 |
Lisinopril | MMP-9 |