Table 2.
Characteristics of survivors of childhood astroglial tumors eligible for study by vision status
| Characteristic | Vision without impairment (n=446) | Vision with impairment (n=102) | Bilateral blindness (n=39) | P-value |
|---|---|---|---|---|
| Age at Interview [n (%)] | ||||
| <30 years | 186 (41.7) | 58 (56.9) | 20 (51.3) | 0.08 |
| 30-39 years | 205 (46.0) | 34 (33.3) | 16 (41.0) | |
| ≥40 years | 55 (12.3) | 10 (9.8) | 3 (7.7) | |
| Sex [n (%)] | ||||
| Male | 224 (50.2) | 43 (42.2) | 18 (46.2) | 0.32 |
| Female | 222 (49.8) | 59 (57.8) | 21 (53.8) | |
| Age at diagnosis [n (%)] | ||||
| ≤4 years | 138 (30.9) | 54 (52.9) | 18 (46.2) | <0.001 |
| 5-9 years | 105 (23.5) | 18 (17.6) | 11 (28.2) | |
| ≥10 years | 203 (45.5) | 30 (29.4) | 10 (25.6) | |
| Treatment* | ||||
| Surgery [n (%)] | ||||
| Yes | 413 (98.8) | 91 (96.8) | 34 (91.9) | 0.03 |
| No | 5 (1.2) | 3 (3.2) | 3 (8.1) | |
| Chemotherapy [n (%)] | ||||
| Yes | 63 (15.0) | 14 (14.9) | 10 (27.0) | 0.17 |
| No | 356 (85.0) | 80 (85.1) | 27 (73.0) | |
| Radiation [n (%)] | ||||
| Yes | 246 (58.7) | 50 (53.2) | 28 (75.7) | 0.06 |
| No | 173 (41.3) | 44 (46.8) | 9 (24.3) | |
| Age at first vision problem | ||||
| ≤6 years | NA | 56 (54.9) | 17 (43.6) | 0.26 |
| >6 years | NA | 46 (45.1) | 22 (56.4) | |
| Proxy reporting* | ||||
| Yes | 88 (20.0) | 22 (21.8) | 16 (41.0) | 0.01 |
| No | 351 (80.0) | 79 (78.2) | 23 (59.0) | |
*
38 survivors of astroglial tumors have no information on surgery (28 with no vision loss, 8 with some vision loss, 2 with bilateral vision loss). 37 survivors of astroglial tumors have no information on chemotherapy or radiation (27 with no vision loss, 8 with some vision loss, 2 with bilateral vision loss). 8 survivors of astroglial tumor did not answer the question for the proxy reporting (7 with no vision loss, 1 with some vision loss).