Table 3.

Univariate comparison of psychological and socioeconomic outcomes among survivors of childhood astroglial tumors by vision status

Outcome			Vision Category			p value
			Vision without impairment	Vision with impairment	Bilateral blindness
Psychological	Short Form-36
	Physical	impaired	57	11	10	0.06
		not impaired	301	70	21
		OR (95%CI)	reference	0.83(0.41,1.66)	2.52(1.13,5.62)
	Mental	impaired	70	18	4	0.55
		not impaired	288	63	27
		OR (95%CI)	reference	1.18(0.66,2.11)	0.61(0.21,1.80)
	Brief Symptom Inventory-18
	GDI	impaired	47	12	4	0.97
		not impaired	326	77	27
		OR (95%CI)	reference	1.08(0.55,2.14)	1.03(0.34,3.07)
	Depression	impaired	60	17	4	0.70
		not impaired	313	72	27
		OR (95%CI)	reference	1.23(0.68,2.24)	0.77(0.26,2.29)
	Anxiety	impaired	36	7	3	0.85
		not impaired	337	82	28
		OR (95%CI)	reference	0.80(0.34,1.86)	1.00(0.29,3.46)
	Somatization	impaired	48	14	6	0.43
		not impaired	325	75	25
		OR (95%CI)	reference	1.26(0.66,2.41)	1.63(0.63,4.17)
	Cantril Ladder of Life
	Life Satisfaction (present)	impaired	129	25	8	0.46
		not impaired	225	55	22
		OR (95%CI)	reference	0.79(0.47,1.33)	0.63(0.28,1.47)
	NeuroCognitive Questionnaire
	Task Efficiency	impaired	133	40	16	0.049
		not impaired	209	40	12
		OR (95%CI)	reference	1.57(0.96,2.56)	2.10(0.96,4.57)
	Emotional Regulation	impaired	48	12	6	0.56
		not impaired	307	68	24
		OR (95%CI)	reference	1.13(0.57,2.24)	1.60(0.62,4.11)
	Organization	impaired	71	17	7	0.86
		not impaired	283	65	23
		OR (95%CI)	reference	1.04(0.58,1.89)	1.21(0.50,2.94)
	Memory	impaired	91	21	10	0.67
		not impaired	259	60	20
		OR (95%CI)	reference	1.00(0.57,1.73)	1.42(0.64,3.15)
Socioeconomic	Marital Status
	Never Married		275	70	34	<0.001
	Married		170	31	4
	OR (95% CI)		reference	1.40(0.88,2.22)	5.26(1.83,15.07)
	Living Arrangement
	Living Dependently		212	57	31	<0.001
	Living Independently		234	45	8
	OR (95% CI)		reference	1.40(0.91,2.16)	4.28(1.92,9.51)
	Employment Status
	Unemployed		166	43	22	0.05
	Employed		280	59	17
	OR (95% CI)		reference	1.23(0.79,1.90)	2.18(1.13,4.23)
	Income
	Income <=$20,000		269	68	27	0.11
	Income >$20,000		158	28	8
	OR (95% CI)		reference	1.43(0.88,2.31)	1.98(0.88,4.47)
	Education
	Less than College		149	35	22	0.02
	College		290	64	16
	OR (95% CI)		reference	1.06(0.67,1.68)	2.68(1.36,5.25)

OR = odds ratio, 95%CI = 95% confidence interval, GDI = Global Disability Index. Bold text indicates statistical significance (p<0.05)