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. 2016 Jan 28;155:463–469. doi: 10.1007/s10549-016-3690-6

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Sample schedule for translational preplanned analysis, with the 2 comparative analyses indicated: A The agreement of central IHC/FISH assessments versus microarray mRNA readouts by TargetPrint^® of ER, PgR, and HER-2 and B Sub-study to assess whether the differences between mRNA and central pathology could be caused by tumor heterogeneity