Figure 5.

Subthalamic nucleus connectivity in binge drinkers and alcohol use disorders. (A) Independent samples t test to compare region of interest to whole-brain voxel connectivity maps for subthalamic nucleus (STN) between groups revealed reduced connectivity of the STN with both the subgenual cingulate cortex and the inferior parietal cortex (cluster-extent threshold analysis p < .05) compared with age- matched healthy volunteers. (B) A trend toward a positive correlation (p = .058) was observed between weeks abstinent and connectivity between STN and right ventral striatum (VS) in individuals with alcohol use disorder.