Fig. 2.

Relationship between cervical cellular phenotype and preterm birth. (A–C) Examples of three different cellular phenotypes from cervical brushes. (A) Leukocyte population consisting of 9% macrophages (CD13+, CD14+) and 91% PMN (CD13+, CD14−). (B) Leukocyte population consisting solely of PMN. (C) No leukocytes detected. (D) Dot plot showing proportion of host-derived cells expressing CD45 from participants who delivered at term (n = 76), late preterm (34–36 + 6 weeks; n = 12) and early preterm (22–33 + 6 weeks; n = 6). (E) Dot plot showing the proportion of host-derived cells expressing CD14 from the same participants as in (D). Open circles indicate participants who received cerclage after sample donation. Horizontal lines indicate means.