Table 1.

AQP4 in synaptic plasticity.

Study	Genotype	Stimulation paradigm	Pathway	Results
Skucas et al., 2011	WT	TBS HFS LFS	SC-CA1 (in vitro) SC-CA1 (in vitro) SC-CA1 (in vitro)	LTP LTP LTD
	KO	TBS HFS LFS LFS + TrkB-Fc LFS + K252a	SC-CA1 (in vitro) SC-CA1 (in vitro) SC-CA1 (in vitro) SC-CA1 (in vitro) SC-CA1 (in vitro)	Reduced LTP with delayed LTD LTP LTD with delayed LTP LTD LTD
Fan et al., 2013	WT	TBS TBS	SC-CA1 (in vivo) PP-DG (in vivo)	LTP LTP
	KO	TBS TBS	SC-CA1 (in vitro) PP-DG (in vivo)	Reduced LTP Reduced LTP
Yang et al., 2013	WT	TBS TBS + Cef TBS + DHK	PP-DG (in vivo) PP-DG (in vivo) PP-DG (in vivo)	LTP LTP Reduced LTP
	KO	TBS TBS + Cef	PP-DG (in vivo) PP-DG (in vivo)	Reduced LTP LTP
Li et al., 2012	WT	HFS	Thalamo-LA	LTP
	KO	HFS HFS + Cef	Thalamo-LA Thalamo-LA	Reduced LTP LTP

Comparisons of synaptic potentiation in wild-type (WT) and KO mice.