Table 2.

Summary of findings from Morris water maze.

Study	Findings
Skucas et al., 2011	1. No significant differences between genotypes
Liu et al., 2012	1. No significant differences between genotypes during the visible platform test. 2. No significant differences between genotypes and treatment during the hidden platform test. 3. KO-treated animals had longer escape latency and swim distance. 4. KO-treated mice had higher random swim pattern. 5. KO-treated mice spent less time in target quadrant.
Fan et al., 2013	1. KO mice had shorter swim path in earlier stages of training. 2. KO mice had longer escape latency. 3. KO mice spent less time in target quadrant. 4. No significant differences in performance between genotypes during the visible platform task.
Zhang et al., 2013	1. No significant differences in escape latency between genotypes (hidden platform). 2. KO mice traveled shorter distances (hidden platform). 3. KO mice had significantly decreased swimming distance and velocity (hidden platform). 4. KO mice displayed gradual reduction in travel length (non-platform). 5. No significant differences between genotypes for quadrant preference (non-platform). 6. No significant differences between genotypes in escape latency, swimming, distance, and swimming velocity during cued platform task (hidden platform). 7. Wild-type mice had greater distance traveled compared to KO mice on first day of cued platform task (non-platform). 8. WT mice had increased swimming velocity compared to KO mice on first day of cued platform task (non-platform). 9. No significant differences in escape latency and swimming velocity between genotypes on second day of cued platform task (hidden platform and non-platform).

Comparison of findings from the Morris water maze in WT and KO mice.