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. 2016 Feb 10;2016:9379840. doi: 10.1155/2016/9379840

Figure 3.

Figure 3

Dynamics of the pro- and anti-inflammatory cytokines IL-1β (a), IL-6 (b), and IL-10 (c) in the crevicular periodontal fluid (pg/mL). The experimental group (Exp, n = 39) was treated with conventional periodontal treatment plus topical daily application of fermented papaya gel into gingival pockets; the control group (Ctr, n = 45) received conventional periodontal treatment for the same period of time. Healthy donors: n = 25. The content of cytokines in the crevicular periodontal fluid was quantified by ELISA method using corresponding monoclonal antibodies. Values are represented as mean and standard deviation of the mean (SD). IL-1β: interleukin 1β; IL-6: interleukin 6; and IL-10: interleukin 10. ∗ P < 0.05 versus analogous day of treatment in the control group. #   P < 0.05 versus healthy donors.