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. 2016 Feb 24;6:21453. doi: 10.1038/srep21453

Table 2. EC₅₀ values of D-amino acid substituted and Asn1 substituted/modified peptides for GALR2 and GALR3.

Substitution/Modification	GALR2		GALR3
Substitution/Modification	EC₅₀(nM)	E_max(Fold induction)	EC₅₀(nM)	E_max(Fold induction)
dN1	21.38 ± 5.54	15.22	38.90 ± 8.00	36.80
dW2	100.00 ± 18.71	16.94	138.04 ± 23.22	33.01
dT3	NM	NM	NM	NM
dA4	97.72 ± 18.29	16.5	112.20 ± 23.07	27.51
dA6	208.93 ± 26.96^a	17.14	316.23 ± 47.07^a	31.76
dY9	NM	NM	NM	NM
dL10	NM	NM	NM	NM
dA12	1230.26 ± 158.75^a	17.19	1412.54 ± 210.27^a	37.2
dQa14	77.62 ± 15.97	15.89	323.59 ± 66.55^a	33.88
pQ1	35.01 ± 7.82	15.85	61.66 ± 10.37	33.08
Ac-N1	58.88 ± 11.02	16.73	81.28 ± 16.71	31.01
PEG-N1	61.65 ± 16.99	14.99	173.78 ± 25.87	31.39
Cit1	61.66 ± 19.00	16.26	251.19 ± 64.98	30.40
Fmoc	77.62 ± 15.97	15.24	125.89 ± 25.89	31.77

^aP < 0.05 vs. WT SPX, NM, Not Measurable.