. 2016 Feb 24;6:21453. doi: 10.1038/srep21453

Table 3. Half-life activity of SPX and SPX mutant peptides in serum.

Peptide	Half-life activity(h) in FBS	Peptide	Half-life activity(h) in FBS	Half-life activity(h) in Human Serum
SPX	4.1 ± 0.5	N5A7F11P13 (Qu)	2.6 ± 0.2	2.0 ± 0.2
Fmoc-SPX	14.2 ± 0.2^a	dN1-Qu	4.2 ± 0.1^a	2.9 ± 0.1^a
PEG-SPX	12.5 ± 0.5^a	PEG-Qu	5.7 ± 0.6^a	ND
Ac-N1	8.7 ± 0.6^a	Fmoc-Qu	6.1 ± 0.2^a	4.9 ± 0.1^a
dN1	10.3 ± 0.3^a	Fmoc-Qu-dQ14	8.4 ± 0.3^a	6.3 ± 0.1^a
dA4	8.7 ± 0.4^a	Fmoc-Qu-dA4-dQ14	11.8 ± 0.2^a	8.8 ± 0.2^a
dW2	4.5 ± 0.6	PEG-Qu-dA4-dQ14	ND	6.0 ± 0.2 ^a
dQ14	5.6 ± 0.2^a

^aP < 0.05 vs. WT SPX or Qu; ND, Not determined.