Table 5.
Experimental groups | Dose (mg/kg) | Prostaglandin E2(pg/mg protin) | NO (μM/g tissue) |
---|---|---|---|
Normal (untreated) | - | 188.39 ± 4.66** | 43.06 ± 4.83** |
Vehicle + ethanol | - | 159.90 ± 6.49## | 22.25 ± 1.65## |
Ranitidine + ethanol | 100 | 186.88 ± 3.39** | 45.73 ± 4.22** |
EAF + ethanol | 100 | 178.12 ± 5.07 | 42.61 ± 2.25** |
250 | 191.94 ± 5.24*** | 47.25 ± 4.46*** | |
500 | 201.07 ± 4.20*** | 56.47 ± 4.61*** |
Values are expressed as mean ± SEM for six animals in each group. One way ANOVA was followed by Dunnett's post hoc test, *p < 0.05, **p < 0.01, and ***p < 0.001 as compared to the vehicle group. Student’s t-test was performed for comparing normal and vehicle group, significant at## p < 0.01