Table 6.
Diagnostic performance of parameters associated with preload dependence-related hypotension in univariate analysis
| Parameter | AUC [CI95%] | Optimal cutoff | Se [CI95%] | Sp [CI95%] | FP | FN | PPV | NPV | PLR | NLR | Youden index |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PVPI at IHD onset | 0.68† [0.53–0.83] | 1.6 | 0.91 [0.59–1.00] | 0.53 [0.42–0.63] | 42 | 1 | 0.19 | 0.98 | 1.93 | 0.17 | 0.44 |
| Mechanical ventilation at IHD onset | 0.69† [0.54–0.85] | NA | 0.64 [0.32–0.88] | 0.75 [0.65–0.83] | 24 | 4 | 0.23 | 0.95 | 2.55 | 0.15 | 0.39 |
| HR at IHD onset (min-1) | 0.60 [0.38–0.81] | 105 | 0.36 [0.11–0.69] | 0.91 [0.83–0.96] | 9 | 7 | 0.31 | 0.93 | 3.88 | 0.70 | 0.27 |
| Dialysate sodium concentration at IHD onset (mmol.L-1) | 0.63 [0.45–0.81] | 145 | 0.82 [0.48–0.98] | 0.45 [0.45–0.55] | 53 | 2 | 0.15 | 0.96 | 1.48 | 0.41 | 0.27 |
| SAPS II | 0.46 [0.30–0.62] | 38 | 0.91 [0.59–1.00] | 0.27 [0.19–0.37] | 53 | 2 | 0.13 | 0.96 | 1.24 | 0.34 | 0.18 |
AUC area under the curve, CI 95% 95 % confidence interval, FP false positive, FN false negative, HR heart rate, NA not applicable, NLR negative likelihood ratio, NPV negative predictive value, PLR positive likelihood ratio, PPV positive predictive value, PVPI pulmonary vascular permeability index, SAPS II Simplified Acute Physiology Score II, Se sensitivity, Sp specificity
†Area under the curve significantly different from 0.5