Fig. 1.

Effect of contextual fear conditioning (Experiment 1). a Experimental protocol for contextual fear conditioning training. Hippocampus samples were collected at 0, 30, 60, 90, 120 min after contextual fear conditioning training. b Representative western blots for the acetylation of H3K14 in the hippocampus and quantification of immunoblot densities for mean (±SEM) acetylated H3K14 at each time point after the contextual fear conditioning training compared with that in mice without training (n = 3–4). c Representative western blots for acetylation of H4K5 in the hippocampus and quantification of immunoblot densities for mean (±SEM) acetylated H4K5 at each time point after the contextual fear conditioning training compared with that in mice without training (n = 3–4). Data are expressed as mean ± SEM. *P < 0.05 compared with no training