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. 2016 Feb 24;16:147. doi: 10.1186/s12885-016-2201-9

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© Lee et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Kaplan-Meier plots illustrating survival outcomes in patients treated with afatinib or erlotinib as 2^nd tyrosine-kinase inhibitor (TKI) therapy after previous failure to first-generation TKI and chemotherapy. a. Progression-free survival (PFS) in the afatinib and erlotinib group. b. Overall survival (OS) in the afatinib and erlotinib group. c. PFS comparing those whose time to progression to 1^st TKI therapy was ≥18 months versus those whose time to progression to 1^st TKI therapy was <18 months