Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 24;35:36. doi: 10.1186/s13046-016-0310-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Dorward et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — Migration and invasion. a, HT29 cells treated with 160 μM or 320 μM AqB013 had a significantly reduced migration compared to vehicle control. b, HCT-116 cells treated with up to 320 μM AqB013 showed no significant effect on wound closure. c, the effect of AqB013 on HT29 cell invasion (n = 3) measured by an increase in sphere size (%) relative to vehicle control: in spheres treated with 80 μM or 160 μM of AqB013 there was a significant decrease in invasion at 144 hours compared with vehicle. d, HCT-116 cells treated with up to 320 μM AqB013 (n = 3) showed no significant effect on invasion. ** p = 0.004; ***p < 0.001 ****p < 0.0001. e, AqB013 treatment up to 320 μM had no effect on cell proliferation of HCT-116, at 160 μM AqB013 HT29 showed 17% reduced proliferation (*p = 0.03 ANOVA). Proliferation measured in absorbance units at 490 nm. The error bars show standard error of the mean