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. 2016 Feb 24;35:36. doi: 10.1186/s13046-016-0310-6

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© Dorward et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Angiogenesis assay. HUVEC tube-forming assay measured by the number of junctions: a, untreated HUVEC; b, vehicle treated HUVEC; c, HUVEC treated with 40 μM AqB013; d, HUVEC treated with 80 μM AqB013 (40 x magnification, scale bar = 0.5 mm); e, graph shows significant inhibition of endothelial tube formation by AqB013 at 40 μM and 80 μM, **p <0.01, ****p < 0.0001 respectively (ANOVA). f, AqB013 treatment had no effect on proliferation of HUVECs