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. 2016 Feb 24;17:101. doi: 10.1186/s12859-016-0955-3

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© Fujimoto et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Examples of a high quality homology (a) and false-positive homology (b) clusters (OD_S data set) classified by meta-classifier w/ logistic regression. All sequences within the homology cluster (a) belong to one protein family (FAM81A1-like protein). The sequence in the false-positive homology cluster indicated by the arrow represents Aprataxin and PNK-like factor whereas other sequences represent tyrosyl-DNA phosphodiesterase