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. 2016 Feb 24;9:43. doi: 10.1186/s13068-016-0455-8

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© MacDonald et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Substrate specificity and overall activity of mutant lyases. The substrate specificity ratio (R_M/G), defined as the ratio of poly-ManA activity over poly-GulA activity, with respect to overall poly-ManA activity for each mutant lyase. Mutants were found to group in four general categories as discussed in the text. Note that 100 % activity was taken as the activity of WT against poly-ManA