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. 2016 Feb 24;5:6. doi: 10.1186/s40164-016-0035-4

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© Murray et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Expression of p53 following UVA irradiation in melanocytes and melanoma. Cell lines were irradiated with 100 kJ/m² UVA, then mRNA transcript relative expression (RE) at baseline and 1, 4, 24, and 48 h post-irradiation was determined. a RE of p53 mRNA transcript. Significance compared to melanocytes (HEMaLP) determined by Mann–Whitney U test. *p < 0.05. Points mean of triplicate determinations of three independent experiments; bars ± SEM. b Western blot of p53 for all cell lines before and after UVA. Blots are representative of duplicate blots run for all proteins and cell lines