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. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Dev Biol. 2015 Jan 13;399(2):237–248. doi: 10.1016/j.ydbio.2014.12.034

Figure 4. Timecourse of pancreatic destruction in cftr mutants.

Figure 4

(A,B) Transverse section of Tg(ptf1a:GFP) expression marking the acinar cells in (A) WT and (B) cftr mutant samples. (C,D) Transverse section at 14 dpf of (C) WT and (D) cftr mutant pancreas marked by ela:GFP expression. (E,F) Transverse section of (E) WT and (F) cftr mutant samples expressing ela:GFP in the acini demonstrating loss of pancreatic acinar tissue at 16 dpf. (G,H) Transverse section of (G) WT and (H) cftr mutant samples expressing ela:GFP in the pancreas at 22 dpf with severe pancreatic destruction. Arrow indicates absent acinar tissue. Scale bars = 50 µm.