Table 2.
Period-specific means and percent changes in the PAH metabolites among the three Olympic periods
| Pre-Olympics | During-Olympics | Post-Olympics | During-Pre Olympics |
Post-During Olympics |
|||
|---|---|---|---|---|---|---|---|
| GMa (95% CI) | GM (95% CI) | GM (95% CI) | % change | 95% CI | % change | 95% CI | |
| Creatinine-unadjusted | |||||||
| 1&2-amino-naphthalene, pg/µl | 0.34 (0.26, 0.45) | 0.24 (0.19, 0.32) | 0.27 (0.17, 0.42) | −29 | (−46, −6) | 11 | (−39, 103) |
| 1-amino-pyrene, pg/µl | 0.11 (0.076, 0.16) | 0.099 (0.070, 0.14) | 0.11 (0.063, 0.19) | −10 | (−34, 22) | 10 | (−46, 124) |
| 1-hydroxy-pyrene, pg/µl | 0.37 (0.28, 0.48) | 0.26 (0.20, 0.33) | 0.20 (0.13, 0.30) | −30* | (−44, −11) | −23 | (−54, 30) |
| Creatinine-standardizedb | |||||||
| 1&2-amino-naphthalene, pg/µg creatinine | 0.48 (0.36, 0.65) | 0.47 (0.36, 0.63) | 0.61 (0.38, 0.97) | −2 | (−27, 31) | 28 | (−32, 142) |
| 1-amino-pyrene, pg/µg creatinine | 0.16 (0.11, 0.22) | 0.19 (0.14, 0.27) | 0.25 (0.15, 0.42) | 22 | (−9, 63) | 31 | (−33, 153) |
| 1-hydroxy-pyrene, pg/µg creatinine | 0.53 (0.44, 0.63) | 0.50 (0.42, 0.60) | 0.46 (0.35, 0.60) | −5 | (−19, 12) | −9 | (−37, 32) |
| Creatinine-independentc | |||||||
| 1&2-amino-naphthalene, pg/µl | 0.31 (0.23, 0.41) | 0.24 (0.19, 0.31) | 0.30 (0.20, 0.47) | −23 | (−41, 2) | 26 | (−30, 127) |
| 1-amino-pyrene, pg/µl | 0.096 (0.067, 0.14) | 0.098 (0.071, 0.14) | 0.13 (0.080, 0.22) | 2 | (−24, 37) | 37 | (−30, 167) |
| 1-hydroxy-pyrene, pg/µl | 0.30 (0.25, 0.37) | 0.25 (0.21, 0.31) | 0.26 (0.19, 0.36) | −16 | (−30, 0) | 3 | (−31, 54) |
GM: Geometric mean. Marker was log-transformed, and geometric means (median) and 95% confident intervals were provided.
Standardizing the PAH metabolites with creatinine by dividing the concentrations of the metabolites with that of creatinine.
Controlling creatinine as an independent variable in the mixed-effects models.
p<.008