Table 2.
Graph diameter and closeness centrality
| Largest connected network | Sub-network of included articles | |||
|---|---|---|---|---|
| GD | CCR | GD | CCR | |
| ACE Inhibitors | 7 | 1~5 | 3 | 1~3 |
| ADHD | 10 | 1~7 | 2 | 1~2 |
| Antihistamines | 8 | 1~6 | 3 | 1~3 |
| Atypical Antipsychotics | 8 | 1~6 | 7 | 1~5 |
| Beta Blockers | 8 | 1~6 | 4 | 1~4 |
| Calcium Channel Blockers | 8 | 1~6 | 7 | 1~5 |
| Estrogens | 7 | 1~5 | 6 | 1~4 |
| NSAIDS | 11 | 1~9 | 3 | 1~3 |
| Opioids | 7 | 1~5 | 3 | 1~3 |
| Oral Hypoglycemics | 5 | 1~4 | 5 | 1~4 |
| Proton Pump Inhibitors | 8 | 1~7 | 3 | 1~3 |
| Skeletal Muscle Relaxants | 13 | 1~9 | 1a | 1~1 |
| Statins | 9 | 1~6 | 4 | 1~4 |
| Triptans | 10 | 1~7 | 5 | 1~4 |
| Urinary Incontinence | 8 | 1~6 | 4 | 1~3 |
| Antibiotic | 6 | 1~5 | 3 | 1~3 |
| Antineoplastic | 9 | 1~7 | 4 | 1~3 |
| Antiretrovirals | 6 | 1~5 | 3 | 1~3 |
| Hearing Loss | 11 | 1~8 | 2 | 1~2 |
| Leukemia | 11 | 1~8 | 2 | 1~2 |
| Average | 8.26 | 1~6 | 3.84* | 1~3 |
GD = Graph Diameter; CCR= Closeness Centrality Range.
a
=Fracture network, only 2 out of 9 nodes are connects. Therefore, the report was not included in the average value.
*
Significant smaller than the largest connected network (p<0.001)