Table 4.
The range of p-values (minimum, average, maximum) for associations matching the same SNP and gold-standard defined phenotype across three methods of defining case/control status.
| Phenotype | Phecode p-value min | Phecode p-value avg | Phecode p-value max | 5 Digit p-value min | 5 Digit p-value avg | 5 Digit p-value max | 3 Digit p-value min | 3 Digit p-value avg | 3 Digit p-value max |
|---|---|---|---|---|---|---|---|---|---|
| T2DM | 1.01E-04 | 7.54E-04 | 9.81E-05 | 1.01E-04 | 7.54E-04 | 9.87E-05 | 1.00E-04 | 6.84E-04 | 9.80E-05 |
| ACS | 2.54E-04 | 5.88E-03 | 9.25E-03 | 1.16E-03 | 3.54E-03 | 9.10E-03 | 5.10E-04 | 3.28E-03 | 8.38E-03 |
| Non-Obstr uctive CAD | 1.59E-04 | 2.60E-03 | 9.93E-03 | 1.86E-03 | 4.76E-03 | 7.88E-03 | 1.87E-03 | 4.80E-03 | 7.94E-03 |
| Obesity | 1.05E-04 | 3.72E-03 | 4.56E-05 | 1.21E-04 | 3.25E-03 | 9.77E-06 | 1.07E-04 | 3.87E-03 | 1.83E-05 |
| Obstructive CAD | 1.59E-04 | 3.21E-03 | 3.70E-05 | 1.38E-03 | 5.58E-03 | 9.38E-03 | 1.40E-03 | 5.67E-03 | 9.51E-03 |